⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18612967 | 0.73 | — | — | |
| SCHEMBL1721841 | 0.71 | — | — | |
| SCHEMBL1334304 | 0.71 | — | — | |
| SCHEMBL15750890 | 0.71 | — | — | |
| SCHEMBL28909 | 0.71 | — | — | |
| SCHEMBL8068886 | 0.71 | — | — | |
| SCHEMBL5610835 | 0.71 | — | — | |
| SCHEMBL28876554 | 0.71 | — | — | |
| SCHEMBL1705442 | 0.69 | — | — | |
| SCHEMBL4215190 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10100076-B2 | Modified nucleosides for the treatment of viral infections and abnormal cellular proliferation | GILEAD PHARMASSET LLC (US) | 2018-10-16 | — | — | US | disclosed |
| WO-2016057500-A1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2016-04-14 | — | — | WO | disclosed |
| US-9216960-B2 | Spiro[2.4]heptanes for treatment of Flaviviridae infections | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2015-12-22 | — | — | US | disclosed |
| US-20150079036-A1 | Spiro[2.4]heptanes for Treatment of Flaviviridae Infections | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2015-03-19 | — | — | US | disclosed |
| US-8946242-B2 | Spiro[2.4]heptanes for treatment of flaviviridae infections | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2015-02-03 | — | — | US | disclosed |
| US-8921384-B2 | Spiro[2.4]heptanes for treatment of flaviviridae infections | UNVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| EP-2814816-A2 | SPIRO [2.4]HEPTANES FOR TREATMENT OF FLAVIVIRIDAE INFECTIONS | University Of Georgia Research Foundation, Inc. (US) | 2014-12-24 | — | — | EP | disclosed |
| US-20140140958-A1 | Spiro[2.4]heptanes for Treatment of Flaviviridae Infections | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2014-05-22 | — | — | US | disclosed |
| US-20140140957-A1 | Spiro[2.4]heptanes for Treatment of Flaviviridae Infections | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2014-05-22 | — | — | US | disclosed |
| US-8673926-B2 | Spiro[2.4]heptanes for treatment of flaviviridae infections | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2014-03-18 | — | — | US | disclosed |
| US-20130224152-A1 | Spiro[2.4]heptanes for Treatment of Flaviviridae Infections | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-08-29 | — | — | US | disclosed |
| WO-2013123138-A2 | SPIRO [2.4]HEPTANES FOR TREATMENT OF FLAVIVIRIDAE INFECTIONS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-08-22 | — | — | WO | disclosed |
| EP-1670787-B1 | CYTOKINE INHIBITORS | ITHERX PHARMA INC (US) | 2012-05-30 | — | — | EP | disclosed |
| US-20110269707-A1 | Modified nucleosides for the treatment of viral infections and abnormal cellullar proliferation | PHARMASSET, INC. | 2011-11-03 | — | — | US | disclosed |
| EP-2251015-A1 | Modified nucleosides for the treatment of viral infections and abnormal cellular proliferation | Pharmasset, Inc. (US) | 2010-11-17 | — | — | EP | disclosed |
| US-20090306095-A1 | COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY | 2009-12-10 | — | — | US | disclosed |
| EP-1411954-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | Pharmasset Limited (BB) | 2004-04-28 | — | — | EP | disclosed |
| US-20030087873-A1 | Modified nucleosides for the treatment of viral infections and abnormal cellular proliferation | PHARMASSET, INC. | 2003-05-08 | — | — | US | disclosed |
| WO-2002032920-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | PHARMASSET LIMITED (BB) | 2002-04-25 | — | — | WO | disclosed |
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |