SCHEMBL25777267

SCHEMBL25777267

C[C@H](CC(=O)O)CC(=O)c1c(CCCCOCc2cccc(Cl)c2)n(C)c2ncc(Cl)cc12

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ OXER1 Q8TDS5 19/20 0.57
▸ MAOB P27338 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25777311 0.94 OXER1 (0.62) OXER1
SCHEMBL25771317 0.94 OXER1 (0.53) OXER1MAOB
SCHEMBL25774022 0.94 OXER1 (0.49) OXER1
SCHEMBL25774566 0.92 OXER1 (0.52) OXER1MAOB
SCHEMBL25777386 0.91 OXER1 (0.51) OXER1
SCHEMBL25774235 0.91 OXER1 (0.51) OXER1MAOB
SCHEMBL25773212 0.91 OXER1 (0.51) OXER1MAOB
SCHEMBL25772602 0.91 OXER1 (0.51) OXER1MAOB
SCHEMBL25774320 0.91 OXER1 (0.52) OXER1MAOB
SCHEMBL25770330 0.90 OXER1 (0.66) OXER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023115203-A1 OXER1 ANTAGONISTS AND USES THEREOF FAIRHAVEN PHARMACEUTICALS INC. (CA) 2023-06-29 — — WO disclosed
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