SCHEMBL2577779

SCHEMBL2577779

C=C[CH]N1CCCC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16582051 0.93 BRD4 (0.33)
SCHEMBL16582041 0.91 HRH3 (0.34)
SCHEMBL10869 0.81
SCHEMBL5473091 0.81 BRD4 (0.42)
SCHEMBL722881 0.79
SCHEMBL21051154 0.79
SCHEMBL3484158 0.79
Methane SCHEMBL21774706 0.79
SCHEMBL21051147 0.79
Ethylene SCHEMBL15224389 0.79 BRD4 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2671884-B1 New 6,11-dihydro-5H-benzo[d]imidazo[1,2-a]azepines derivatives as histamine H4 receptor ligands BIOPROJET SOC CIV (FR) 2015-03-25 EP claimed
EP-2245014-B1 UREA DERIVATIVES OF BENZOMORPHANES AND RELATED SCAFFOLDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE BOEHRINGER INGELHEIM INT (DE) 2011-11-02 EP claimed
EP-1707202-A1 Organic compounds Speedel Experimenta AG (CH) 2006-10-04 EP claimed
CN-1211583-A Polyorganosiloxanes with dialdoxyorganosiloxy end groups HUELS SILICONE GMBH (DE) 1999-03-24 CN claimed
EP-0238883-A1 Oxabicycloheptane derivatives, pharmaceutical composition and use SUNTORY LIMITED (JP) 1987-09-30 EP claimed
EP-1707206-A1 Piperazine derivates for the inhibition of beta-secretase, cathepsin D, plasmepsin ll and HIV protease and for the treatment of malaria, Alzeheimer and AIDS Speedel Experimenta AG (CH) 2006-10-04 EP disclosed
EP-1707202-A1 Organic compounds Speedel Experimenta AG (CH) 2006-10-04 EP disclosed
CN-1183201-C Akoxyl cross-link RTV1 silicon rubber mixture �ȿ˻�ѧ�ɷ����޹�˾ 2005-01-05 CN disclosed
CN-1211583-A Polyorganosiloxanes with dialdoxyorganosiloxy end groups HUELS SILICONE GMBH (DE) 1999-03-24 CN disclosed
CN-1203247-A Akoxyl cross-link RTV1 silicon rubber mixture HUELS SILICONE GMBH (DE) 1998-12-30 CN disclosed
WO-1997017181-A1 METHOD FOR PRODUCING AN OPTICAL ARTICLE IN A MOLD SEALED UNDER VACUUM UCB, S.A. (BE) 1997-05-15 WO disclosed
WO-1997017182-A1 METHOD FOR PRODUCING AN OPTICAL ARTICLE USING VISIBLE LIGHT RADIATION UCB, S.A. (BE) 1997-05-15 WO disclosed
EP-0238883-B1 OXABICYCLOHEPTANE DERIVATIVES, PHARMACEUTICAL COMPOSITION AND USE SUNTORY LIMITED (JP) 1990-05-09 EP disclosed
US-4713453-A TREATMENT OF BRAIN DISORDERS Suntori Limited (JP) 1987-12-15 US disclosed
EP-0238883-A1 Oxabicycloheptane derivatives, pharmaceutical composition and use SUNTORY LIMITED (JP) 1987-09-30 EP disclosed