Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.89 |
| ▸ | TP53 | P04637 | 4/20 | 0.72 |
| ▸ | THRB | P10828 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 6/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25780435 | 0.95 | IDO1 (0.90) | IDO1KCNH2TP53THRBMAPT | |
| SCHEMBL22397379 | 0.94 | IDO1 (1.00) | IDO1KCNH2TP53THRBMAPT | |
| SCHEMBL25779978 | 0.93 | IDO1 (0.87) | IDO1KCNH2TP53THRBMAPT | |
| SCHEMBL25780453 | 0.91 | IDO1 (0.84) | IDO1KCNH2TP53THRBMAPT | |
| SCHEMBL25779984 | 0.89 | IDO1 (0.81) | IDO1KCNH2TP53THRBMAPT | |
| SCHEMBL31492881 | 0.89 | IDO1 (0.90) | IDO1KCNH2TP53THRBMAPT | |
| SCHEMBL22397378 | 0.89 | IDO1 (0.90) | IDO1KCNH2TP53THRBMAPT | |
| SCHEMBL25780815 | 0.88 | IDO1 (0.79) | IDO1KCNH2TP53THRBMAPT | |
| SCHEMBL25779974 | 0.88 | IDO1 (0.78) | IDO1KCNH2TP53THRBMAPT | |
| SCHEMBL25780414 | 0.87 | IDO1 (0.77) | IDO1KCNH2TP53THRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125473-A1 | INDOLINE COMPOUNDS AND DERIVATIVES THEREOF, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国药科大学 | 2023-07-06 | — | — | WO | disclosed |