Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25780379 | 0.87 | HSD17B10 (0.49) | HSD17B10AKT1TSHRLMNACHEK1 | |
| SCHEMBL18341944 | 0.87 | HSD17B10 (0.51) | HSD17B10AKT1TSHRLMNACHEK1 | |
| SCHEMBL25781162 | 0.82 | HSD17B10 (0.47) | HSD17B10AKT1TSHRLMNACHEK1 | |
| SCHEMBL3741042 | 0.79 | HSD17B10 (0.57) | HSD17B10AKT1TSHRLMNACHEK1 | |
| SCHEMBL985935 | 0.79 | HSD17B10 (0.57) | HSD17B10AKT1TSHRLMNAMAPT | |
| SCHEMBL18341910 | 0.76 | AKT1 (0.59) | HSD17B10AKT1TSHRCHEK1MAPT | |
| SCHEMBL25781012 | 0.76 | HSD17B10 (0.46) | HSD17B10AKT1TSHRLMNACHEK1 | |
| SCHEMBL29559920 | 0.76 | HRH4 (0.47) | CACNA1HHRH4 | |
| SCHEMBL22866666 | 0.76 | HRH4 (0.47) | CACNA1HHRH4 | |
| SCHEMBL20293286 | 0.75 | HSD17B10 (0.53) | HSD17B10AKT1TSHRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109902-A1 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF IN MEDICINE | 海思科医药集团股份有限公司 | 2023-06-22 | — | — | WO | disclosed |