Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.35 |
| ▸ | CSF1R | P07333 | 4/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17914481 | 0.79 | GRM5 (0.46) | ADORA2AADORA1POLBNPC1RAB9A | |
| SCHEMBL19531663 | 0.76 | BRD4 (0.44) | NTRK1CSF1RNTRK2GAALMNA | |
| SCHEMBL19538841 | 0.75 | NTRK1 (0.34) | NTRK1CSF1RNTRK2GAALMNA | |
| SCHEMBL12872413 | 0.73 | NPC1 (0.49) | SRCPOLBNPC1RAB9AGAA | |
| SCHEMBL18193669 | 0.73 | ADORA2A (0.36) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL14805626 | 0.73 | KDM4E (0.35) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL21285478 | 0.72 | SRC (0.36) | SRCPDE2APDE10AMAPTMEN1 | |
| SCHEMBL19251148 | 0.71 | HRH4 (0.37) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL18211613 | 0.70 | MAPT (0.42) | SRCPOLBNPC1RAB9AGAA | |
| SCHEMBL20251321 | 0.70 | SRC (0.45) | SRCADORA2AADORA1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |