⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14510741 | 0.67 | — | — | |
| SCHEMBL18183417 | 0.65 | MEN1 (0.47) | — | |
| SCHEMBL2221307 | 0.64 | — | — | |
| Ammonia Solution, Strong SCHEMBL3344999 | 0.62 | MEN1 (0.58) | — | |
| SCHEMBL11688286 | 0.62 | MEN1 (0.39) | — | |
| SCHEMBL5666713 | 0.62 | — | — | |
| Mipimazole SCHEMBL2734172 | 0.62 | — | — | |
| SCHEMBL3500678 | 0.62 | — | — | |
| SCHEMBL9180300 | 0.62 | — | — | |
| SCHEMBL9168191 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370539-B1 | HIV INHIBITING N-AMINOIMIDAZOLE DERIVATIVES | LEUVEN K U RES & DEV (BE) | 2011-11-09 | — | — | EP | disclosed |
| US-7049332-B2 | HIV inhibiting N-aminoimidazole derivatives | K. U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2006-05-23 | — | — | US | disclosed |
| US-20040122024-A1 | Hiv inhibiting n-aminoimidazole derivatives | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2004-06-24 | — | — | US | disclosed |
| EP-1370539-A1 | HIV INHIBITING N-AMINOIMIDAZOLE DERIVATIVES | K.U. Leuven Research and Development (BE) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002068395-A1 | HIV INHIBITING N-AMINOIMIDAZOLE DERIVATIVES | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2002-09-06 | — | — | WO | disclosed |
| US-5356895-A | Aminoguanidine derivatives; preventing food spoilage, animal aging | THE ROCKEFELLER UNIVERSITY (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0327919-B1 | METHOD AND AGENTS FOR PREVENTING STAINING OF TEETH | THE ROCKEFELLER UNIVERSITY (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5140048-A | Inhibitors of nonenzymatic cross-linking | THE ROCKEFELLER UNIVERSITY (US) | 1992-08-18 | — | — | US | disclosed |
| US-5128122-A | Nitrogen compound | THE ROCKEFELLER UNIVERSITY (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0280868-B1 | IMIDAZO- AND TRIAZOLOTHIADIAZINES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND THEIR USE AS WELL AS SOME OF THE INTERMEDIATES OBTAINED DURING THE PREPARATION OF SAID COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-17 | — | — | EP | disclosed |
| US-4983604-A | Aminoguanidine derivatives | THE ROCKEFELLER UNIVERSITY (US) | 1991-01-08 | — | — | US | disclosed |
| US-4908446-A | Inhibitors of nonenzymatic cross-linking | THE ROCKEFELLER UNIVERSITY (US) | 1990-03-13 | — | — | US | disclosed |
| US-4891374-A | INFLAMMATORY RHEUMATIC DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-02 | — | — | US | disclosed |
| EP-0327919-A2 | Method and agents for preventing staining of teeth | THE ROCKEFELLER UNIVERSITY (US) | 1989-08-16 | — | — | EP | disclosed |
| EP-0316852-A2 | Inhibitors of nonenzymatic cross-linking | THE ROCKEFELLER UNIVERSITY (US) | 1989-05-24 | — | — | EP | disclosed |
| EP-0280868-A2 | Imidazo- and triazolothiadiazines, process for their preparation, medicaments containing them and their use as well as some of the intermediates obtained during the preparation of said compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-09-07 | — | — | EP | disclosed |
| US-4273679-A | Aluminum alloys having a high reducing capacity and preparation thereof | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1981-06-16 | — | — | US | disclosed |