Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 17/20 | 0.76 |
| ▸ | MTOR | P42345 | 10/20 | 0.76 |
| ▸ | ATRIP | Q8WXE1 | 9/20 | 0.76 |
| ▸ | PRKDC | P78527 | 2/20 | 0.76 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.76 |
| ▸ | LCK | P06239 | 1/20 | 0.76 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.76 |
| ▸ | ATM | Q13315 | 1/20 | 0.76 |
| ▸ | PDCD1 | Q15116 | 12/20 | 0.64 |
| ▸ | CD274 | Q9NZQ7 | 12/20 | 0.64 |
| ▸ | CHEK1 | O14757 | 11/20 | 0.64 |
| ▸ | TAF1 | P21675 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25244279 | 0.87 | ATR (0.74) | ATRMTORATRIPPRKDCNUAK1 | |
| SCHEMBL25789858 | 0.87 | ATR (0.74) | ATRMTORATRIPPRKDCNUAK1 | |
| SCHEMBL25080622 | 0.86 | ATR (1.00) | ATRMTORATRIPPRKDCNUAK1 | |
| SCHEMBL25080620 | 0.86 | ATR (1.00) | ATRMTORATRIPPRKDCNUAK1 | |
| SCHEMBL25791120 | 0.83 | ATR (0.59) | ATRMTORATRIPPRKDCNUAK1 | |
| SCHEMBL25251800 | 0.82 | ATR (0.74) | ATRMTORATRIPPRKDCNUAK1 | |
| SCHEMBL30443443 | 0.82 | ATR (0.74) | ATRMTORATRIPPRKDCNUAK1 | |
| SCHEMBL25292692 | 0.82 | ATR (0.74) | ATRMTORATRIPPRKDCNUAK1 | |
| SCHEMBL25789616 | 0.79 | ATR (0.86) | ATRMTORATRIPPRKDCNUAK1 | |
| SCHEMBL25789619 | 0.79 | ATR (0.86) | ATRMTORATRIPPRKDCNUAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116594-A1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海安诺达生物科技有限公司 | 2023-06-29 | — | — | WO | disclosed |