Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 6/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 11/20 | 0.38 |
| ▸ | ATRIP | Q8WXE1 | 6/20 | 0.38 |
| ▸ | MTOR | P42345 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25791094 | 0.84 | ATR (0.44) | ATRATRIPMTORPDCD1CD274 | |
| SCHEMBL25790981 | 0.82 | PDE4D (0.43) | PDE4DGABRA1DRD4ATRATRIP | |
| SCHEMBL25080796 | 0.82 | HRH3 (0.45) | ATRATRIPMTOR | |
| SCHEMBL25080710 | 0.82 | HRH3 (0.45) | ATRATRIPMTOR | |
| SCHEMBL25246628 | 0.81 | ATR (0.43) | PDE4DGABRA1DRD4ATRATRIP | |
| SCHEMBL30443084 | 0.81 | ATR (0.43) | PDE4DGABRA1DRD4ATRATRIP | |
| SCHEMBL25285745 | 0.81 | ATR (0.43) | PDE4DGABRA1DRD4ATRATRIP | |
| SCHEMBL30443862 | 0.78 | ATR (0.56) | ATRATRIPMTORPDCD1CD274 | |
| SCHEMBL25246480 | 0.78 | ATR (0.56) | ATRATRIPMTORPDCD1CD274 | |
| SCHEMBL25287943 | 0.78 | ATR (0.56) | ATRATRIPMTORPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116594-A1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海安诺达生物科技有限公司 | 2023-06-29 | — | — | WO | disclosed |