Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31150269 | 1.00 | HRH3 (0.37) | HRH3SYKRAF1BRAFPDE2A | |
| SCHEMBL20836320 | 0.93 | CA1 (0.33) | HRH3ACACB | |
| SCHEMBL31673370 | 0.93 | CA1 (0.33) | HRH3ACACB | |
| SCHEMBL17669544 | 0.91 | HRH3 (0.36) | HRH3SYKRAF1BRAFPDE2A | |
| SCHEMBL16583636 | 0.81 | PDE10A (0.36) | HRH3SYKRAF1BRAFPDE10A | |
| SCHEMBL31150291 | 0.81 | CYP2D6 (0.39) | HRH3ACACB | |
| SCHEMBL25793697 | 0.81 | CYP2D6 (0.39) | HRH3ACACB | |
| SCHEMBL14230903 | 0.80 | CA1 (0.47) | HRH3APPACACB | |
| SCHEMBL31150293 | 0.79 | PDE2A (0.39) | HRH3PDE2A | |
| SCHEMBL25793699 | 0.79 | PDE2A (0.39) | HRH3PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131116-A1 | CARBONYL BRIDGED HETEROCYCLIC COMPOUND, AND COMPOSITION AND APPLICATION THEREOF | 北京赛特明强医药科技有限公司 | 2023-07-13 | — | — | WO | disclosed |