Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2579398 | 0.90 | PTGDR2 (0.34) | PTGDR2PTGES | |
| SCHEMBL2572394 | 0.86 | PTGDR2 (0.48) | PTGDR2P2RX3 | |
| SCHEMBL2570601 | 0.84 | PTGDR2 (0.40) | PTGDR2PTGES | |
| SCHEMBL534060 | 0.82 | AR (0.36) | PTGDR2 | |
| SCHEMBL2577124 | 0.77 | PTGDR2 (0.54) | PTGDR2 | |
| SCHEMBL2572541 | 0.76 | PTGDR2 (0.39) | PTGDR2 | |
| SCHEMBL2572974 | 0.75 | PTGDR2 (0.38) | PTGDR2 | |
| SCHEMBL14046780 | 0.73 | PTGDR2 (0.49) | PTGDR2P2RX3 | |
| SCHEMBL3780664 | 0.73 | PTGDR2 (0.54) | PTGDR2P2RX3 | |
| SCHEMBL2578291 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139881-B1 | QUINOLINES AND THEIR THERAPEUTIC USE | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2011-11-09 | — | — | EP | claimed |