Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 6/20 | 0.37 |
| ▸ | JAK3 | P52333 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2575212 | 0.93 | KMT2A (0.48) | KMT2AALDH1A1MEN1HSD17B10NUDT1 | |
| SCHEMBL3267220 | 0.83 | KMT2A (0.56) | KMT2AALDH1A1MEN1HSD17B10NUDT1 | |
| Hydrochloric Acid SCHEMBL27223443 | 0.82 | KMT2A (0.55) | KMT2AALDH1A1MEN1HSD17B10NUDT1 | |
| SCHEMBL9921991 | 0.75 | KMT2A (0.51) | KMT2AALDH1A1MEN1HSD17B10NUDT1 | |
| SCHEMBL9918656 | 0.72 | KMT2A (0.49) | KMT2AALDH1A1MEN1HSD17B10NUDT1 | |
| SCHEMBL31575794 | 0.72 | KMT2A (0.46) | KMT2AALDH1A1MEN1HSD17B10NUDT1 | |
| SCHEMBL2564768 | 0.71 | GRM6 (0.41) | KMT2AALDH1A1NUDT1TSHRGRM6 | |
| SCHEMBL2572856 | 0.71 | KDM4E (0.39) | KMT2AALDH1A1MEN1HSD17B10KDM4E | |
| SCHEMBL1156163 | 0.69 | KMT2A (0.58) | KMT2AALDH1A1MEN1HSD17B10NUDT1 | |
| SCHEMBL1457077 | 0.68 | TSHR (0.61) | KMT2AALDH1A1MEN1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382218-A1 | DELTA-5-DESATURASE INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010087467-A1 | DELTA-5-DESATURASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |