Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.54 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 7/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2818149 | 1.00 | ACE (0.56) | ACEFOLH1NAALAD2MMEACE2 | |
| SCHEMBL8823272 | 0.87 | ACE (0.58) | ACEFOLH1NAALAD2MMEACE2 | |
| SCHEMBL953389 | 0.87 | FOLH1 (0.56) | ACEFOLH1NAALAD2MMEACE2 | |
| SCHEMBL8823270 | 0.87 | ACE (0.58) | ACEFOLH1NAALAD2MMEACE2 | |
| SCHEMBL838885 | 0.87 | FOLH1 (0.56) | ACEFOLH1NAALAD2MMEACE2 | |
| SCHEMBL27802669 | 0.85 | ACE (0.53) | ACEFOLH1NAALAD2MMEACE2 | |
| SCHEMBL17393507 | 0.84 | ACE (0.56) | ACEFOLH1NAALAD2MMEACE2 | |
| SCHEMBL7136038 | 0.79 | FOLH1 (0.51) | ACEFOLH1NAALAD2MMEACE2 | |
| SCHEMBL1008925 | 0.78 | FOLH1 (0.56) | ACEFOLH1NAALAD2MMEACE2 | |
| SCHEMBL160418 | 0.78 | FOLH1 (0.60) | ACEFOLH1NAALAD2MMEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101723849-B | Novel 18F labeled amino acid derivatives, preparation method and application thereof in tumor imaging | UNIV BEIJING NORMAL | 2012-11-21 | — | — | CN | disclosed |
| US-8050477-B2 | Radiation therapy flanning procedure | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2011-11-01 | — | — | US | disclosed |
| US-20090028408-A1 | RADIATION THERAPY FLANNING PROCEDURE | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2009-01-29 | — | — | US | disclosed |
| EP-1981593-A2 | IMPROVED RADIATION THERAPY PLANNING PROCEDURE | Philips Intellectual Property & Standards GmbH (DE) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007088492-A2 | IMPROVED RADIATION THERAPY PLANNING PROCEDURE | PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH (DE) | 2007-08-09 | — | — | WO | disclosed |