Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25796716 | 0.81 | C5AR1 (0.41) | NR1H2ADORA1ESR2C5AR1F12 | |
| SCHEMBL18852439 | 0.79 | ESR2 (0.39) | NR1H2ADORA1ESR2DDB1CRBN | |
| SCHEMBL25796720 | 0.78 | CYP2C19 (0.33) | BRD4CREBBP | |
| SCHEMBL15635176 | 0.76 | ADORA1 (0.49) | NR1H2ADORA1ESR2DDB1CRBN | |
| SCHEMBL22909708 | 0.75 | F12 (0.49) | NR1H2ADORA1ESR2C5AR1F12 | |
| SCHEMBL17795594 | 0.73 | ADORA1 (0.40) | NR1H2ADORA1ESR2DDB1CRBN | |
| SCHEMBL14555911 | 0.72 | ADORA1 (0.41) | NR1H2ADORA1ESR2DDB1CRBN | |
| SCHEMBL25211071 | 0.72 | DDB1 (0.41) | NR1H2ADORA1ESR2DDB1CRBN | |
| SCHEMBL21255363 | 0.72 | DDB1 (0.37) | NR1H2ADORA1ESR2DDB1CRBN | |
| SCHEMBL18359467 | 0.71 | ESR2 (0.41) | NR1H2ADORA1ESR2DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116812-A1 | SULFONYLUREA COMPOUND | 瑞石生物医药有限公司 | 2023-06-29 | — | — | WO | disclosed |