Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 9/20 | 0.46 |
| ▸ | JAK2 | O60674 | 7/20 | 0.46 |
| ▸ | SYK | P43405 | 5/20 | 0.45 |
| ▸ | CD63 | P08962 | 2/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.44 |
| ▸ | BTK | Q06187 | 3/20 | 0.42 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.41 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | CIT | O14578 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | GAK | O14976 | 1/20 | 0.39 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | BUB1 | O43683 | 1/20 | 0.39 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.39 |
| ▸ | STK16 | O75716 | 1/20 | 0.39 |
| ▸ | STK10 | O94804 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25245168 | 0.92 | BTK (0.46) | SYKTLR8TLR7TLR9BTK | |
| SCHEMBL25297478 | 0.88 | SYK (0.49) | SYKBTKEGFRMAPK8MAPK9 | |
| SCHEMBL25287571 | 0.87 | PDGFRB (0.47) | BTKEGFRPDGFRBFLT3TNK2 | |
| SCHEMBL15551432 | 0.85 | SYK (0.58) | JAK2SYKCD63 | |
| SCHEMBL25242788 | 0.84 | BTK (0.43) | SYKTLR8TLR7TLR9BTK | |
| SCHEMBL25291927 | 0.84 | PDGFRB (0.50) | SYKTLR8TLR7TLR9BTK | |
| SCHEMBL30299467 | 0.84 | SYK (0.63) | TBK1JAK2SYKCD63TLR8 | |
| SCHEMBL25249235 | 0.84 | SYK (0.63) | TBK1JAK2SYKCD63TLR8 | |
| SCHEMBL25246067 | 0.83 | BTK (0.44) | SYKBTKPDGFRBFLT3MAPK8 | |
| SCHEMBL25797064 | 0.83 | SYK (0.50) | JAK2SYKCD63 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203042-A1 | COMPOUNDS AND THEIR USES AS SPLEEN TYROSINE KINASE INHIBITORS | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2023-06-29 | — | — | US | disclosed |
| US-20230203042-A1 | COMPOUNDS AND THEIR USES AS SPLEEN TYROSINE KINASE INHIBITORS | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203042-A1 | COMPOUNDS AND THEIR USES AS SPLEEN TYROSINE KINASE INHIBITORS | SYK, BTK, LCK | TBK1 84/4885JAK2 17/4885SYK 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.