Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28011694 | 0.89 | — | — | |
| SCHEMBL172387 | 0.80 | — | — | |
| SCHEMBL172424 | 0.80 | — | — | |
| SCHEMBL10291757 | 0.80 | — | — | |
| SCHEMBL24930782 | 0.78 | SLC6A4 (0.32) | SLC6A4 | |
| SCHEMBL22882514 | 0.78 | SLC6A4 (0.32) | SLC6A4 | |
| SCHEMBL19101519 | 0.78 | SLC6A4 (0.32) | SLC6A4 | |
| SCHEMBL25802592 | 0.77 | — | — | |
| SCHEMBL20613668 | 0.76 | SLC6A4 (0.31) | SLC6A4 | |
| SCHEMBL22303375 | 0.76 | SLC6A4 (0.31) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452456-B1 | BICYCLIC MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2023-07-05 | — | — | EP | disclosed |