Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22090718 | 0.91 | HPGD (0.45) | HPGDMAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL30660087 | 0.91 | HPGD (0.45) | HPGDMAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL22090709 | 0.91 | HPGD (0.45) | HPGDMAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL30660105 | 0.91 | HPGD (0.45) | HPGDMAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL22090689 | 0.91 | HPGD (0.45) | HPGDMAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL30660088 | 0.91 | HPGD (0.45) | HPGDMAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL22090511 | 0.89 | HPGD (0.43) | HPGDMAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL30660086 | 0.89 | HPGD (0.43) | HPGDMAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL21822864 | 0.89 | TSHR (0.47) | HPGDMAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL21822411 | 0.89 | TSHR (0.44) | HPGDMAPTCYP3A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3894402-B1 | N-CONTAINING CHROMEN-4-ONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2023-07-05 | — | — | EP | disclosed |