Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634745 | 0.84 | CNR2 (0.35) | PDCD1CD274 | |
| SCHEMBL31094902 | 0.84 | CNR2 (0.35) | PDCD1CD274 | |
| SCHEMBL25801334 | 0.83 | KDM4E (0.30) | — | |
| SCHEMBL25801394 | 0.83 | — | — | |
| SCHEMBL24151357 | 0.83 | PDCD1 (0.34) | PDCD1CD274 | |
| SCHEMBL25801365 | 0.83 | PDCD1 (0.35) | PDCD1CD274 | |
| SCHEMBL25801320 | 0.81 | FFAR1 (0.34) | — | |
| SCHEMBL24152315 | 0.80 | KDM4E (0.30) | — | |
| SCHEMBL25801194 | 0.75 | PDE10A (0.38) | PDCD1CD274 | |
| SCHEMBL23901971 | 0.72 | KDM4E (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212180-A1 | SUBSTITUTED PYRAZINE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212180-A1 | SUBSTITUTED PYRAZINE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | PTPN5, PTPN1, PTPN2 | PDCD1 1172/4885CD274 2525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.