Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25802341 | 0.89 | PTPN11 (0.33) | PTPN11 | |
| SCHEMBL25802277 | 0.79 | PTPN11 (0.33) | PTPN11KCNH2 | |
| SCHEMBL22393733 | 0.79 | HTR2A (0.38) | KCNH2 | |
| SCHEMBL24151656 | 0.73 | PTPN11 (0.34) | PTPN11KCNH2 | |
| SCHEMBL24388859 | 0.72 | PTPN11 (0.36) | PTPN11KCNH2 | |
| SCHEMBL25803172 | 0.71 | PTPN11 (0.34) | PTPN11KCNH2 | |
| SCHEMBL25801832 | 0.71 | KCNH2 (0.33) | PTPN11KCNH2 | |
| SCHEMBL24375017 | 0.71 | — | — | |
| SCHEMBL25802340 | 0.69 | PTPN11 (0.34) | PTPN11KCNH2 | |
| SCHEMBL24878788 | 0.69 | PTPN11 (0.46) | PTPN11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212180-A1 | SUBSTITUTED PYRAZINE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212180-A1 | SUBSTITUTED PYRAZINE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | PTPN5, PTPN1, PTPN2 | PTPN11 5/4885KCNH2 2405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.