⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25802030 | 0.91 | — | — | |
| SCHEMBL25801764 | 0.90 | HDAC1 (0.30) | — | |
| SCHEMBL25801826 | 0.90 | HDAC1 (0.30) | — | |
| SCHEMBL23578565 | 0.90 | HDAC1 (0.30) | — | |
| SCHEMBL23578101 | 0.88 | HDAC1 (0.31) | — | |
| SCHEMBL23578531 | 0.85 | CHRM2 (0.35) | — | |
| SCHEMBL23578249 | 0.85 | CHRM2 (0.35) | — | |
| SCHEMBL23578160 | 0.85 | HDAC1 (0.32) | — | |
| SCHEMBL23578580 | 0.85 | CHRM2 (0.35) | — | |
| SCHEMBL25801924 | 0.85 | CHRM2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219907-A1 | CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-07-13 | — | — | US | disclosed |
| US-20230219907-A1 | CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-07-13 | — | — | US | disclosed |
| EP-4081511-A1 | CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES | Sitryx Therapeutics Limited (GB) | 2022-11-02 | — | — | EP | disclosed |