Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 14/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 11/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2577642 | 0.82 | S1PR1 (0.64) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL1334359 | 0.78 | S1PR1 (0.56) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL1335776 | 0.76 | S1PR1 (0.58) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL2274576 | 0.70 | S1PR1 (0.45) | S1PR1S1PR5 | |
| SCHEMBL1334297 | 0.69 | S1PR1 (0.67) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL28644781 | 0.68 | S1PR1 (0.60) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL3749519 | 0.68 | S1PR1 (0.98) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL13415797 | 0.67 | S1PR1 (1.00) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL1336650 | 0.67 | S1PR1 (0.67) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL1334354 | 0.67 | S1PR1 (0.70) | S1PR1S1PR5S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382211-B1 | PYRAZOLE-I, 2, 4 -OXAD IAZOLE DERIVATIVES AS S.PHING0SINE-1-PH0SPHATE AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2012-12-19 | — | — | EP | disclosed |
| EP-2382211-A1 | PYRAZOLE-I, 2, 4 -OXAD IAZOLE DERIVATIVES AS S.PHING0SINE-1-PH0SPHATE AGONISTS | Bristol-Myers Squibb Company (US) | 2011-11-02 | — | — | EP | disclosed |