Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CPT2 | P23786 | 1/20 | 0.45 |
| ▸ | CPT1A | P50416 | 1/20 | 0.45 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22043970 | 0.91 | STING1 (0.61) | STING1SMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL22044779 | 0.91 | STING1 (0.61) | STING1SMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL21990175 | 0.91 | STING1 (0.61) | STING1SMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL22044387 | 0.89 | STING1 (0.59) | STING1SMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL22044775 | 0.89 | STING1 (0.59) | STING1SMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL22043972 | 0.89 | STING1 (0.73) | STING1SMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL25943521 | 0.88 | STING1 (0.57) | STING1SMN1; SMN2ALDH1A1MAPTCPT2 | |
| SCHEMBL22043975 | 0.88 | STING1 (0.57) | STING1SMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL21990159 | 0.87 | STING1 (0.93) | STING1SMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL25942338 | 0.86 | STING1 (0.55) | STING1SMN1; SMN2ALDH1A1TSHRCPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147597-A2 | ALLOSTERIC STING MODULATORS AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |