SCHEMBL25810615

SCHEMBL25810615

Cc1cc(F)cc(NC2CCC(=O)NC2=O)c1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 20/20 0.63
CRBN Q96SW2 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22117964 0.84 CRBN (0.65) DDB1CRBN
Hydrochloric Acid SCHEMBL22117687 0.83 CRBN (0.63) DDB1CRBN
SCHEMBL23551636 0.83 CRBN (0.62) DDB1CRBN
SCHEMBL27274933 0.83 DDB1 (0.59) DDB1CRBN
SCHEMBL30338067 0.82 CRBN (0.58) DDB1CRBN
SCHEMBL28637008 0.82 CRBN (0.58) DDB1CRBN
Hydrochloric Acid SCHEMBL30338377 0.81 CRBN (0.56) DDB1CRBN
SCHEMBL31619865 0.80 CRBN (0.51) DDB1CRBN
SCHEMBL25960989 0.80 CRBN (0.69) DDB1CRBN
SCHEMBL21965746 0.79 DDB1 (0.72) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023116934-A1 KRASG12D PROTEIN HYDROLYSIS REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 苏州泽璟生物制药股份有限公司 2023-06-29 WO disclosed