Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.61 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 10/20 | 0.41 |
| ▸ | TOP1 | P11387 | 2/20 | 0.40 |
| ▸ | HRAS | P01112 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30125594 | 0.95 | HDAC1 (0.59) | HDAC1HDAC2HDAC8ERBB2NR3C1 | |
| SCHEMBL25805949 | 0.92 | HDAC1 (0.57) | HDAC1HDAC2HDAC8ERBB2NR3C1 | |
| SCHEMBL25701096 | 0.92 | HDAC1 (0.62) | HDAC1HDAC2HDAC8ERBB2NR3C1 | |
| SCHEMBL25248804 | 0.91 | HDAC1 (0.59) | HDAC1HDAC2HDAC8ERBB2NR3C1 | |
| SCHEMBL23728545 | 0.91 | HDAC1 (0.61) | HDAC1HDAC2HDAC8ERBB2NR3C1 | |
| SCHEMBL19423270 | 0.91 | HDAC1 (0.61) | HDAC1HDAC2HDAC8ERBB2NR3C1 | |
| SCHEMBL25212056 | 0.91 | HDAC1 (0.60) | HDAC1HDAC2HDAC8ERBB2NR3C1 | |
| SCHEMBL23728852 | 0.91 | HDAC1 (0.58) | HDAC1HDAC2HDAC8ERBB2NR3C1 | |
| SCHEMBL30693805 | 0.91 | HDAC1 (0.58) | HDAC1HDAC2HDAC8ERBB2NR3C1 | |
| SCHEMBL23718079 | 0.90 | HDAC1 (0.65) | HDAC1HDAC2HDAC8ERBB2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133284-A2 | COMPOUNDS AND METHODS FOR TREATING FRIEDREICH'S ATAXIA | Design Therapeutics, Inc. (US) | 2023-07-13 | — | — | WO | disclosed |