Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 5/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26288084 | 1.00 | PIK3CD (0.40) | PIK3CDJAK3NAMPTEPHX2PIK3R1 | |
| SCHEMBL26296771 | 1.00 | PIK3CD (0.40) | PIK3CDJAK3NAMPTEPHX2PIK3R1 | |
| SCHEMBL22874736 | 0.91 | EPHX2 (0.42) | PIK3CDNAMPTEPHX2KMT2ATLR9 | |
| SCHEMBL25628747 | 0.91 | EPHX2 (0.42) | PIK3CDNAMPTEPHX2KMT2ATLR9 | |
| SCHEMBL22875072 | 0.91 | EPHX2 (0.42) | PIK3CDNAMPTEPHX2KMT2ATLR9 | |
| SCHEMBL26296202 | 0.89 | HRH3 (0.37) | PIK3CDKDM5AKMT2AIDH1 | |
| SCHEMBL18745326 | 0.82 | HPGD (0.45) | MAPT | |
| SCHEMBL26790447 | 0.82 | HPGD (0.45) | MAPT | |
| SCHEMBL22874738 | 0.82 | NAMPT (0.40) | NAMPTEPHX2KMT2ATLR9TLR8 | |
| SCHEMBL17540496 | 0.82 | EPHX2 (0.44) | EPHX2KDM5ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023172737-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-09-14 | — | — | WO | disclosed |
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |