Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25811593 | 0.81 | — | — | |
| SCHEMBL25811878 | 0.79 | MEN1 (0.35) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL25811567 | 0.67 | CYP3A4 (0.38) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL25811605 | 0.66 | — | — | |
| SCHEMBL12234302 | 0.65 | ENTPD5 (0.53) | CYP3A4 | |
| SCHEMBL12234029 | 0.65 | ENTPD5 (0.53) | CYP3A4 | |
| SCHEMBL12234286 | 0.65 | ENTPD5 (0.53) | CYP3A4 | |
| SCHEMBL12234310 | 0.65 | ENTPD5 (0.53) | CYP3A4 | |
| SCHEMBL12234031 | 0.65 | ENTPD5 (0.53) | CYP3A4 | |
| SCHEMBL11997251 | 0.65 | ENTPD5 (0.53) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125989-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |