Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.67 |
| ▸ | HTR1D | P28221 | 3/20 | 0.66 |
| ▸ | HTR1B | P28222 | 3/20 | 0.66 |
| ▸ | HTR2C | P28335 | 2/20 | 0.66 |
| ▸ | HTR7 | P34969 | 2/20 | 0.66 |
| ▸ | HTR6 | P50406 | 2/20 | 0.66 |
| ▸ | HTR1A | P08908 | 2/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.66 |
| ▸ | HTR1E | P28566 | 1/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 2/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25811159 | 0.91 | HTR2A (0.70) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| Hydrochloric Acid SCHEMBL18425954 | 0.90 | HTR2A (0.68) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| SCHEMBL28417220 | 0.89 | HTR2A (0.71) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| SCHEMBL30282858 | 0.85 | HTR2A (0.75) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| SCHEMBL16973850 | 0.85 | HTR2A (0.75) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| SCHEMBL21292843 | 0.85 | HTR2A (0.75) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| SCHEMBL29411007 | 0.85 | HTR2A (0.75) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| SCHEMBL18822721 | 0.85 | HTR2A (0.74) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| Hydrochloric Acid SCHEMBL18426570 | 0.84 | HTR2A (0.73) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| SCHEMBL7863739 | 0.84 | HTR2A (0.68) | HTR2AHTR1DHTR1BHTR2CHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125376-A1 | FUSED BICYCLIC HETEROARYL AMIDE COMPOUND AS PROTEIN AGGREGATION INHIBITOR | 上海京新生物医药有限公司 | 2023-07-06 | — | — | WO | disclosed |