SCHEMBL25812020

SCHEMBL25812020

Clc1ccc(Br)c([C@@H]2CO2)c1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.35
CHRNA4 P43681 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
TSHR P16473 2/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
MAP3K14 Q99558 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21184717 0.84 MAP3K14 (0.36) CHRNB2CHRNA4TAAR1TSHRHTT
SCHEMBL7049820 0.79 TP53 (0.42) CHRNB2CHRNA4TSHR
SCHEMBL478331 0.78 NPC1 (0.36) CHRNB2CHRNA4TSHRMAPK1HTT
SCHEMBL30601262 0.78 NPC1 (0.36) CHRNB2CHRNA4TSHRMAPK1HTT
SCHEMBL13551058 0.76 KDM1A (0.36) CHRNB2CHRNA4
SCHEMBL29439088 0.75 HTR2A (0.49) TSHRHTT
SCHEMBL4311498 0.75 HTR2A (0.49) TSHRHTT
SCHEMBL4311675 0.75 HTR2A (0.49) TSHRHTT
SCHEMBL1583058 0.75 HTR2A (0.49) TSHRHTT
SCHEMBL16291407 0.75 TAAR1 (0.42) CHRNB2CHRNA4TAAR1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4212517-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC ELEMENT, COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE Samsung SDI Co., Ltd. (KR) 2023-07-19 EP disclosed