SCHEMBL25812302

SCHEMBL25812302

C=C(C)C(=O)OCCC[Si](OC)(OC)OC(C)C

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
THRB P10828 1/20 0.40
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133182 0.92 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28617940 0.91 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL26849839 0.90 TSHR (0.41) TSHRTHRBPOLBAPEX1HTT
Alcohol SCHEMBL29001782 0.88 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28957948 0.88 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5446210 0.87 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL15276 0.87 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL27154327 0.86 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
Hydrogen Sulfide SCHEMBL329768 0.85 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23437 0.85 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4263868-A1 NANOARRAYS AND METHODS OF USE THEREOF Singular Genomics Systems, Inc. (US) 2023-10-25 EP claimed
WO-2022192671-A1 NANOARRAYS AND METHODS OF USE THEREOF Singular Genomics Systems, Inc. (US) 2022-09-15 WO claimed
CN-110938089-A Preparation method of silane for synthesizing water-based acrylic emulsion and silane 湖北新蓝天新材料股份有限公司 2020-03-31 CN claimed
US-20230399692-A1 NUCLEIC ACID DELIVERY SCAFFOLDS FIRST-CITIZENS BANK & TRUST COMPANY 2023-12-14 US disclosed
EP-4263868-A1 NANOARRAYS AND METHODS OF USE THEREOF Singular Genomics Systems, Inc. (US) 2023-10-25 EP disclosed
US-11795505-B2 Nucleic acid delivery scaffolds Singular Genomics Systems, Inc. (US) 2023-10-24 US disclosed
US-20230287491-A1 NUCLEIC ACID DELIVERY SCAFFOLDS FIRST-CITIZENS BANK & TRUST COMPANY 2023-09-14 US disclosed
US-20230203579-A1 NANOARRAYS AND METHODS OF USE THEREOF FIRST-CITIZENS BANK & TRUST COMPANY 2023-06-29 US disclosed
WO-2022192671-A1 NANOARRAYS AND METHODS OF USE THEREOF Singular Genomics Systems, Inc. (US) 2022-09-15 WO disclosed
CN-110938089-A Preparation method of silane for synthesizing water-based acrylic emulsion and silane 湖北新蓝天新材料股份有限公司 2020-03-31 CN disclosed