Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 10/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2571794 | 0.88 | CNR2 (0.36) | BRD4CNR2CNR1SCN10A | |
| SCHEMBL2578712 | 0.86 | CNR2 (0.38) | BRD4CNR2CNR1 | |
| SCHEMBL2566394 | 0.83 | CNR2 (0.37) | BRD4CNR2CNR1 | |
| SCHEMBL2581266 | 0.82 | CNR2 (0.37) | CNR2CNR1 | |
| SCHEMBL2571231 | 0.81 | CNR2 (0.37) | BRD4CNR2CNR1 | |
| SCHEMBL2567727 | 0.81 | CNR2 (0.37) | BRD4CNR2CNR1 | |
| SCHEMBL2570666 | 0.81 | CNR2 (0.36) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL2570499 | 0.80 | CNR2 (0.37) | BRD4CNR2CNR1 | |
| SCHEMBL2568547 | 0.80 | CNR2 (0.37) | CNR2CNR1 | |
| SCHEMBL2571965 | 0.79 | CNR2 (0.36) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2090570-B1 | IMIDAZOLE DERIVATIVE | KYOWA HAKKO KIRIN CO LTD (JP) | 2011-11-09 | — | — | EP | disclosed |
| EP-2090570-A1 | IMIDAZOLE DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-08-19 | — | — | EP | disclosed |