Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | ACACA | Q13085 | 3/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | CSF3R | Q99062 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21289112 | 1.00 | POLB (0.43) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL22814289 | 0.96 | POLB (0.40) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL21891666 | 0.93 | POLB (0.46) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL27423567 | 0.90 | POLB (0.38) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL22101128 | 0.88 | POLB (0.42) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL21254293 | 0.86 | POLB (0.40) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL22360394 | 0.86 | POLB (0.40) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL22842242 | 0.86 | POLB (0.42) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL22592264 | 0.86 | POLB (0.39) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL19559099 | 0.86 | POLB (0.39) | POLBAPEX1HTTTDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209567-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2023-07-12 | — | — | EP | disclosed |