Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL116499 | 1.00 | — | — | |
| Bromide SCHEMBL1029370 | 1.00 | — | — | |
| Bromide SCHEMBL1031102 | 1.00 | — | — | |
| Bromide SCHEMBL1030524 | 1.00 | — | — | |
| Bromide SCHEMBL11503584 | 1.00 | — | — | |
| Bromide SCHEMBL1025982 | 1.00 | — | — | |
| Bromide SCHEMBL10427946 | 1.00 | — | — | |
| Bromide SCHEMBL1032276 | 1.00 | — | — | |
| Bromide SCHEMBL10457047 | 1.00 | — | — | |
| Bromide SCHEMBL30602641 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118930518-A | Method for preparing (S) -nicotine by reduction mode | 重庆博腾制药科技股份有限公司 | 2024-11-12 | — | — | CN | claimed |
| CN-115404250-B | Method for preparing (S) -nicotine by reduction mode | 重庆博腾制药科技股份有限公司 | 2024-08-06 | — | — | CN | claimed |
| US-20240141306-A1 | IMINE REDUCTASE MUTANT, CO-EXPRESSED RECOMBINANT ENZYME OF IMINE REDUCTASE AND GLUCOSE DEHYDROGENASE, AND APPLICATIONS THEREOF | PORTON PHARMA SOLUTIONS LTD. (CN) | 2024-05-02 | — | — | US | claimed |
| EP-4361260-A1 | IMINE REDUCTASE MUTANT, CO-EXPRESSED ENZYME OF IMINE REDUCTASE AND GLUCOSE DEHYDROGENASE, AND APPLICATION THEREOF | Porton Pharma Solutions Ltd. (CN) | 2024-05-01 | — | — | EP | claimed |
| US-20240124908-A1 | METHOD FOR PREPARING (S)-NICOTINE BY REDUCTION | PORTON PHARMA SOLUTIONS LTD. (CN) | 2024-04-18 | — | — | US | claimed |
| EP-4349995-A1 | METHOD FOR USING REDUCTION TO PREPARE (S)-NICOTINE | Porton Pharma Solutions Ltd. (CN) | 2024-04-10 | — | — | EP | claimed |
| CN-117751184-A | Imine reductase mutant, imine reductase and glucose dehydrogenase coexpression enzyme and application thereof | 重庆博腾制药科技股份有限公司 | 2024-03-22 | — | — | CN | claimed |
| EP-3600315-B1 | NEW THERAPEUTICAL USE OF H3-LIGANDS | BIOPROJET PHARMA (FR) | 2023-09-06 | — | — | EP | claimed |
| WO-2022268006-A1 | IMINE REDUCTASE MUTANT, CO-EXPRESSED ENZYME OF IMINE REDUCTASE AND GLUCOSE DEHYDROGENASE, AND APPLICATION THEREOF | 陈泽聪 | 2022-12-29 | — | — | WO | claimed |
| CN-115491364-A | Imine reductase mutant, imine reductase and glucose dehydrogenase coexpression enzyme and application thereof | 陈泽聪 | 2022-12-20 | — | — | CN | claimed |
| WO-2022253111-A1 | METHOD FOR USING REDUCTION TO PREPARE (S)-NICOTINE | 重庆博腾制药科技股份有限公司 | 2022-12-08 | — | — | WO | claimed |
| CN-115404250-A | Method for preparing (S) -nicotine by reduction mode | 重庆博腾制药科技股份有限公司 | 2022-11-29 | — | — | CN | claimed |
| US-20260109697-A1 | 4-(IMIDAZO[1,2-A]PYRIDIN-3-YL)-PYRIMIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2026-04-23 | — | — | US | disclosed |
| US-12606537-B2 | Thiophene derivatives | Ryvu Therapeutics S.A. (PL) | 2026-04-21 | — | — | US | disclosed |
| US-20260042753-A1 | INDAZOLYL-ISOXAZOLE DERIVATIVES FOR THE TREATMENT OF DISEASES SUCH AS CANCER | MERCK PATENT GMBH (DE) | 2026-02-12 | — | — | US | disclosed |
| EP-4678750-A1 | REPLICON DNA, CLONING VECTOR, SCREENING KIT, SCREENING METHOD, ANTI-NOBECOVIRUS AGENT, BETA-CORONAVIRUS PROLIFERATION INHIBITOR, PAN BETA-CORONAVIRUS INHIBITOR, VIRUS PROLIFERATION INHIBITOR, HEPATITIS C VIRUS PROLIFERATION INHIBITOR, AND METHOD FOR SCREENING THERAPEUTIC AGENT FOR VIRAL INFECTIOUS DISEASE | Kagoshima University (JP) | 2026-01-14 | — | — | EP | disclosed |
| WO-2001035745-A1 | CONCENTRATED AQUEOUS BROMINE SOLUTIONS AND THEIR PREPARATION | ALBEMARLE CORPORATION (US) | 2001-05-25 | — | — | WO | disclosed |
| WO-2001020996-A1 | BIOCIDAL APPLICATIONS OF CONCENTRATED AQUEOUS BROMINE CHLORIDE SOLUTIONS | ALBEMARLE CORPORATION (US) | 2001-03-29 | — | — | WO | disclosed |
| US-4973547-A | MULTILAYER SILVER HALIDE GRAINS SELECTIVELY ETCHED | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1990-11-27 | — | — | US | disclosed |
| US-3933680-A | ORGANOTIN COMPOUNDS | M & T CHEMICALS INC. (US) | 1976-01-20 | — | — | US | disclosed |