SCHEMBL25816238

SCHEMBL25816238

COC(=O)c1ccc2nc(CN3CCN(c4cccc5c4OCCO5)CC3)n(CC3CCO3)c2c1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 20/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25815551 0.91 GLP1R (0.56) GLP1R
SCHEMBL26518481 0.89 GLP1R (0.58) GLP1R
SCHEMBL25816019 0.89 GLP1R (0.58) GLP1R
SCHEMBL25816249 0.84 GLP1R (0.54) GLP1R
SCHEMBL24186716 0.84 GLP1R (0.54) GLP1R
SCHEMBL24186710 0.84 GLP1R (0.54) GLP1R
SCHEMBL24186582 0.84 GLP1R (0.54) GLP1R
SCHEMBL22062475 0.83 GLP1R (0.57) GLP1R
SCHEMBL25816361 0.83 GLP1R (0.44) GLP1R
SCHEMBL24265271 0.83 GLP1R (0.57) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4209490-A1 FUSED IMIDAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) 2023-07-12 EP disclosed