Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 20/20 | 0.55 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25821255 | 1.00 | GLP1R (0.55) | GLP1RCYP2C8KCNH2HTR2AHTR1A | |
| SCHEMBL25816445 | 0.94 | GLP1R (0.55) | GLP1RCYP2C8KCNH2HTR2AHTR1A | |
| SCHEMBL25815635 | 0.92 | GLP1R (0.64) | GLP1RCYP2C8KCNH2HTR2AHTR1A | |
| SCHEMBL23516172 | 0.91 | GLP1R (0.56) | GLP1RCYP2C8KCNH2HTR2AHTR1A | |
| SCHEMBL25816019 | 0.90 | GLP1R (0.58) | GLP1RCYP2C8KCNH2HTR2AHTR1A | |
| SCHEMBL26518481 | 0.90 | GLP1R (0.58) | GLP1RCYP2C8KCNH2HTR2AHTR1A | |
| SCHEMBL22062475 | 0.90 | GLP1R (0.57) | GLP1RCYP2C8KCNH2HTR2AHTR1A | |
| SCHEMBL25823609 | 0.87 | GLP1R (0.50) | GLP1RCYP2C8KCNH2HTR2AHTR1A | |
| SCHEMBL24186491 | 0.87 | GLP1R (0.55) | GLP1R | |
| SCHEMBL24186445 | 0.87 | GLP1R (0.55) | GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209490-A1 | FUSED IMIDAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2023-07-12 | — | — | EP | disclosed |