Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 9/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.45 |
| ▸ | IKZF2 | Q9UKS7 | 8/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22704098 | 0.90 | HTR2A (0.49) | HTR2AHTR2CHTR2BCRBNCSNK1A1 | |
| SCHEMBL30405557 | 0.85 | CRBN (0.66) | CRBNCSNK1A1IKZF2 | |
| SCHEMBL27232439 | 0.85 | CRBN (0.47) | CRBNCSNK1A1IKZF2PARP10PARP11 | |
| SCHEMBL18270971 | 0.82 | CRBN (0.63) | CRBNCSNK1A1IKZF2 | |
| SCHEMBL20128640 | 0.81 | CRBN (0.63) | HTR2AHTR2CHTR2BCRBNCSNK1A1 | |
| SCHEMBL20766788 | 0.81 | CRBN (0.65) | CRBNCSNK1A1IKZF2 | |
| SCHEMBL20496839 | 0.81 | CRBN (0.46) | CRBNCSNK1A1IKZF2PARP10PARP11 | |
| SCHEMBL20496840 | 0.81 | CRBN (0.46) | CRBNCSNK1A1IKZF2PARP10PARP11 | |
| SCHEMBL18263925 | 0.81 | CRBN (0.65) | CRBNCSNK1A1IKZF2 | |
| SCHEMBL20766790 | 0.81 | CRBN (0.65) | CRBNCSNK1A1IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |