Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.56 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270662 | 1.00 | TLR7 (0.56) | TLR7TLR8NUDT1 | |
| SCHEMBL25296984 | 0.89 | TLR7 (0.67) | TLR7TLR8 | |
| SCHEMBL25257813 | 0.86 | TLR7 (0.54) | TLR7TLR8 | |
| SCHEMBL24538755 | 0.86 | TLR7 (0.69) | TLR7TLR8 | |
| SCHEMBL30876985 | 0.86 | TLR7 (0.69) | TLR7TLR8 | |
| SCHEMBL25257990 | 0.84 | TLR8 (0.43) | TLR7TLR8 | |
| SCHEMBL31270698 | 0.84 | TLR8 (0.43) | TLR7TLR8 | |
| SCHEMBL5344428 | 0.83 | TLR7 (0.72) | TLR7TLR8NUDT1 | |
| SCHEMBL31709368 | 0.83 | TLR7 (0.59) | TLR7TLR8NUDT1 | |
| SCHEMBL31337596 | 0.83 | TLR7 (0.59) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |