Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.48 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | ADA | P00813 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.45 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.45 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23645538 | 0.92 | POLB (0.49) | POLBENPP1P2RY1ADORA1ADA | |
| SCHEMBL19887008 | 0.89 | POLB (0.47) | POLBENPP1P2RY1ADORA1ADA | |
| SCHEMBL15280844 | 0.89 | POLB (0.47) | POLBENPP1P2RY1ADORA1ADA | |
| SCHEMBL24473715 | 0.88 | P2RY1 (0.60) | POLBENPP1P2RY1ADORA1DNPH1 | |
| SCHEMBL22060000 | 0.87 | POLB (0.46) | POLBENPP1P2RY1ADATP53 | |
| SCHEMBL12340917 | 0.84 | POLB (0.53) | POLBENPP1P2RY1ADORA1DNPH1 | |
| SCHEMBL18314959 | 0.82 | ADA (0.53) | POLBENPP1P2RY1ADORA1ADA | |
| SCHEMBL22143020 | 0.82 | ADA (0.53) | POLBENPP1P2RY1ADORA1ADA | |
| SCHEMBL18314960 | 0.82 | POLB (0.49) | POLBENPP1P2RY1ADORA1ADA | |
| SCHEMBL22393564 | 0.81 | POLB (0.52) | POLBENPP1P2RY1ADORA1ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212572-A1 | Guanosine Analogues for Use in Therapeutics Polynucleotides | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2023-07-06 | — | — | US | disclosed |
| US-20230212572-A1 | Guanosine Analogues for Use in Therapeutics Polynucleotides | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2023-07-06 | — | — | US | disclosed |