Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.66 |
| ▸ | GBA1 | P04062 | 12/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25516156 | 1.00 | HRH4 (0.66) | HRH4HRH3GBA1CYP19A1EPHX2 | |
| SCHEMBL94371 | 1.00 | HRH4 (0.66) | HRH4HRH3GBA1CYP19A1EPHX2 | |
| SCHEMBL19501713 | 1.00 | HRH4 (0.66) | HRH4HRH3GBA1CYP19A1EPHX2 | |
| SCHEMBL11318961 | 1.00 | HRH4 (0.66) | HRH4HRH3GBA1CYP19A1EPHX2 | |
| SCHEMBL19663777 | 1.00 | HRH4 (0.66) | HRH4HRH3GBA1CYP19A1EPHX2 | |
| SCHEMBL24675720 | 1.00 | HRH4 (0.66) | HRH4HRH3GBA1CYP19A1EPHX2 | |
| SCHEMBL15944228 | 1.00 | HRH4 (0.66) | HRH4HRH3GBA1CYP19A1EPHX2 | |
| SCHEMBL15203072 | 1.00 | HRH4 (0.66) | HRH4HRH3GBA1CYP19A1EPHX2 | |
| SCHEMBL21959579 | 1.00 | HRH4 (0.66) | HRH4HRH3GBA1CYP19A1EPHX2 | |
| SCHEMBL25516157 | 1.00 | HRH4 (0.66) | HRH4HRH3GBA1CYP19A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129564-A1 | DEGRADERS OF GRK2 AND USES THEREOF | CYGNAL THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |