Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 17/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 6/20 | 1.00 |
| ▸ | SCN1A | P35498 | 2/20 | 1.00 |
| ▸ | SCN5A | Q14524 | 2/20 | 1.00 |
| ▸ | SCN9A | Q15858 | 2/20 | 1.00 |
| ▸ | SCN2A | Q99250 | 2/20 | 1.00 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 1.00 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25567465 | 0.91 | SCN10A (0.84) | SCN10AKCNH2SCN1ASCN5ASCN9A | |
| SCHEMBL25818969 | 0.88 | SCN10A (0.79) | SCN10AKCNH2SCN1ASCN5ASCN9A | |
| SCHEMBL14375985 | 0.77 | SCN10A (0.71) | SCN10AKCNH2SCN1ASCN5ASCN9A | |
| Hydrochloric Acid SCHEMBL20474360 | 0.76 | SCN10A (0.97) | SCN10AKCNH2SCN1ASCN5ASCN9A | |
| SCHEMBL25303086 | 0.75 | SCN10A (0.71) | SCN10AKCNH2SCN1ASCN5ASCN9A | |
| Hydrochloric Acid SCHEMBL18438904 | 0.75 | SCN10A (0.69) | SCN10AKCNH2SCN1ASCN5ASCN9A | |
| SCHEMBL26094793 | 0.74 | TRPV1 (0.68) | SCN10AKCNH2SCN1ASCN5ASCN9A | |
| Bromide SCHEMBL25435849 | 0.74 | SCN10A (0.70) | SCN10AKCNH2SCN1ASCN5ASCN9A | |
| SCHEMBL26095676 | 0.71 | NPY5R (0.66) | SCN10AKCNH2SCN1ASCN5ASCN9A | |
| SCHEMBL18797643 | 0.71 | SCN10A (0.56) | SCN10AKCNH2SCN1ASCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4183778-B1 | ANALGESIC AND ANTIPRURITIC PHARMACEUTICAL COMPOSITION AND APPLICATION METHOD THEREFOR | KEVICI SHANGHAI PHARMACEUTICAL CO LTD (CN) | 2025-07-16 | — | — | EP | claimed |
| US-12318369-B2 | Analgesic and antipruritic pharmacertical composition and application thereof | KEVICI (SHANGHAI) PHARMACEUTICAL CO., LTD. (CN) | 2025-06-03 | — | — | US | claimed |
| US-20240197690-A1 | ANALGESIC AND ANTIPRURITIC PHARMACERTICAL COMPOSITION AND APPLICATION THEREOF | SHANGHAI RUIHUKANG PHARMACEUTICAL PARTNERSHIP (LIMITED PARTNERSHIP) (CN) | 2024-06-20 | — | — | US | claimed |
| US-11938118-B2 | Analgesic and antipruritic pharmaceutical composition and application thereof | SHANGHAI RUIHUKANG PHARMACEUTICAL PARTNERSHIP (LIMITED PARTNERSHIP) (CN) | 2024-03-26 | — | — | US | claimed |
| US-20230201170-A1 | ANALGESIC AND ANTIPRURITIC PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | KEVICI (SHANGHAI) PHARMACEUTICAL CO., LTD. (CN) | 2023-06-29 | — | — | US | claimed |
| EP-4183778-A1 | ANALGESIC AND ANTIPRURITIC PHARMACEUTICAL COMPOSITION AND APPLICATION METHOD THEREFOR | Shanghai Ruihukang Pharmaceutical Partnership (Limited Partnership) (CN) | 2023-05-24 | — | — | EP | claimed |
| CN-114073698-B | Pain-relieving and itching-relieving pharmaceutical composition and application method thereof | 山西泰睿鑫科技有限公司 | 2023-03-31 | — | — | CN | claimed |
| WO-2022037006-A1 | ANALGESIC AND ANTIPRURITIC PHARMACEUTICAL COMPOSITION AND APPLICATION METHOD THEREFOR | 上海市第一康复医院(上海市杨浦区老年医院) | 2022-02-24 | — | — | WO | claimed |
| CN-114073698-A | Pain-relieving and itching-relieving pharmaceutical composition and application method thereof | 上海市第一康复医院(上海市杨浦区老年医院) | 2022-02-22 | — | — | CN | claimed |
| EP-4183778-B1 | ANALGESIC AND ANTIPRURITIC PHARMACEUTICAL COMPOSITION AND APPLICATION METHOD THEREFOR | KEVICI SHANGHAI PHARMACEUTICAL CO LTD (CN) | 2025-07-16 | — | — | EP | disclosed |
| US-12318369-B2 | Analgesic and antipruritic pharmacertical composition and application thereof | KEVICI (SHANGHAI) PHARMACEUTICAL CO., LTD. (CN) | 2025-06-03 | — | — | US | disclosed |
| US-12318369-B2 | Analgesic and antipruritic pharmacertical composition and application thereof | KEVICI (SHANGHAI) PHARMACEUTICAL CO., LTD. (CN) | 2025-06-03 | — | — | US | disclosed |
| US-20240398762-A1 | PHARMACEUTICAL COMPOSITION WITH ANALGESIC AND/OR ANTIPRURITIC FUNCTIONS AND APPLICATION THEREOF | KEVICI (SHANGHAI) PHARMACEUTICAL CO., LTD. (CN) | 2024-12-05 | — | — | US | disclosed |
| EP-4464319-A1 | PHARMACEUTICAL COMPOSITION HAVING ANALGESIC AND/OR ANTIPRURITIC FUNCTION AND USE THEREOF | Pengekiphen Biotech Limited Company (CN) | 2024-11-20 | — | — | EP | disclosed |
| CN-114073698-B | Pain-relieving and itching-relieving pharmaceutical composition and application method thereof | 山西泰睿鑫科技有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-114288289-A | Pharmaceutical composition with analgesic and/or antipruritic functions and application thereof | 昆山彭济凯丰生物科技有限公司 | 2022-04-08 | — | — | CN | disclosed |
| WO-2022037006-A1 | ANALGESIC AND ANTIPRURITIC PHARMACEUTICAL COMPOSITION AND APPLICATION METHOD THEREFOR | 上海市第一康复医院(上海市杨浦区老年医院) | 2022-02-24 | — | — | WO | disclosed |
| WO-2022037006-A1 | ANALGESIC AND ANTIPRURITIC PHARMACEUTICAL COMPOSITION AND APPLICATION METHOD THEREFOR | 上海市第一康复医院(上海市杨浦区老年医院) | 2022-02-24 | — | — | WO | disclosed |
| CN-114073698-A | Pain-relieving and itching-relieving pharmaceutical composition and application method thereof | 上海市第一康复医院(上海市杨浦区老年医院) | 2022-02-22 | — | — | CN | disclosed |
| CN-114073698-A | Pain-relieving and itching-relieving pharmaceutical composition and application method thereof | 上海市第一康复医院(上海市杨浦区老年医院) | 2022-02-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12318369-B2 | Analgesic and antipruritic pharmacertical composition and application thereof | SCN8A, SCN7A, SCN1A | SCN10A 6/4885KCNH2 92/4885SCN1A 3/4885 |
| US-20240398762-A1 | PHARMACEUTICAL COMPOSITION WITH ANALGESIC AND/OR ANTIPRURITIC FUNCTIONS AND APPLICATION THEREOF | SCN7A, SCN8A, SCNN1G | SCN10A 7/4885KCNH2 65/4885SCN1A 4/4885 |
| US-20230201170-A1 | ANALGESIC AND ANTIPRURITIC PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | SCN8A, SCN7A, SCN1A | SCN10A 8/4885KCNH2 77/4885SCN1A 3/4885 |
| US-11938118-B2 | Analgesic and antipruritic pharmaceutical composition and application thereof | SCN8A, SCN7A, SCN1A | SCN10A 8/4885KCNH2 77/4885SCN1A 3/4885 |
| US-20240197690-A1 | ANALGESIC AND ANTIPRURITIC PHARMACERTICAL COMPOSITION AND APPLICATION THEREOF | SCN8A, SCN7A, SCN1A | SCN10A 6/4885KCNH2 92/4885SCN1A 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.