Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | USP2 | O75604 | 2/20 | 0.68 |
| ▸ | DNMT1 | P26358 | 6/20 | 0.63 |
| ▸ | DNMT3A | Q9Y6K1 | 6/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | BRAF | P15056 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | DNMT3L | Q9UJW3 | 4/20 | 0.53 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.50 |
| ▸ | CCNC | P24863 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13335888 | 0.96 | KMT2A (0.74) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| SCHEMBL30232549 | 0.94 | KMT2A (0.78) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| SCHEMBL19151496 | 0.94 | KMT2A (0.78) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| SCHEMBL13335884 | 0.94 | MAPT (0.77) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| SCHEMBL13335886 | 0.89 | KMT2A (0.85) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| SCHEMBL13335917 | 0.89 | DNMT1 (0.69) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| SCHEMBL3076951 | 0.87 | KMT2A (0.67) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| SCHEMBL3076947 | 0.87 | KMT2A (0.67) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| Hydrochloric Acid SCHEMBL1884267 | 0.87 | KMT2A (0.66) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| SCHEMBL13335900 | 0.86 | MAPT (0.66) | KMT2AMAPTUSP2DNMT1DNMT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | KMT2A 4131/4885MAPT 3976/4885USP2 4143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.