Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270620 | 1.00 | TLR7 (0.44) | TLR7TLR8P2RY14 | |
| SCHEMBL31270949 | 0.99 | TLR7 (0.45) | TLR7TLR8P2RY14 | |
| SCHEMBL25820585 | 0.99 | TLR7 (0.45) | TLR7TLR8P2RY14 | |
| SCHEMBL31270869 | 0.90 | TLR7 (0.42) | TLR7TLR8 | |
| SCHEMBL25820109 | 0.90 | TLR7 (0.43) | TLR7TLR8 | |
| SCHEMBL25818922 | 0.90 | TLR7 (0.43) | TLR7TLR8P2RY14 | |
| SCHEMBL31270800 | 0.90 | TLR7 (0.43) | TLR7TLR8P2RY14 | |
| SCHEMBL25301523 | 0.89 | TLR7 (0.49) | TLR7TLR8 | |
| SCHEMBL25301818 | 0.88 | TLR7 (0.50) | TLR7TLR8 | |
| SCHEMBL25820997 | 0.85 | TLR7 (0.41) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |