Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.42 |
| ▸ | PPARD | Q03181 | 13/20 | 0.42 |
| ▸ | PPARG | P37231 | 11/20 | 0.42 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2582904 | 1.00 | PPARA (0.42) | PPARAPPARDPPARGSUV39H2LMNA | |
| SCHEMBL1186192 | 0.91 | PPARA (0.44) | PPARAPPARDPPARGLMNA | |
| SCHEMBL2577180 | 0.91 | PPARA (0.44) | PPARAPPARDPPARGLMNA | |
| SCHEMBL1185682 | 0.91 | PPARA (0.44) | PPARAPPARDPPARGLMNA | |
| SCHEMBL28789660 | 0.83 | IDO1 (0.41) | PPARAPPARDPPARGSUV39H2LMNA | |
| SCHEMBL27821501 | 0.83 | IDO1 (0.41) | PPARAPPARDPPARGSUV39H2LMNA | |
| SCHEMBL1185862 | 0.82 | IDO1 (0.45) | PPARAPPARDPPARGLMNAALDH1A1 | |
| SCHEMBL2583923 | 0.82 | IDO1 (0.45) | PPARAPPARDPPARGLMNAALDH1A1 | |
| SCHEMBL12980519 | 0.81 | IDO1 (0.40) | PPARAPPARDPPARGLMNAALDH1A1 | |
| SCHEMBL2799300 | 0.72 | GAA (0.50) | PPARAPPARGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8049006-B2 | 7-membered ring compound and method of production and pharmaceutical application thereof | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-11-01 | — | — | US | disclosed |