Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 7/20 | 0.63 |
| ▸ | DNMT3A | Q9Y6K1 | 6/20 | 0.63 |
| ▸ | DNMT3L | Q9UJW3 | 4/20 | 0.55 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.55 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | GAK | O14976 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24009937 | 0.94 | DNMT1 (0.58) | DNMT1DNMT3ADNMT3LEHMT1RIPK2 | |
| SCHEMBL30290892 | 0.94 | DNMT1 (0.58) | DNMT1DNMT3ADNMT3LEHMT1RIPK2 | |
| SCHEMBL24006360 | 0.91 | DNMT1 (0.64) | DNMT1DNMT3ADNMT3LEHMT1RIPK2 | |
| SCHEMBL25820587 | 0.90 | DNMT1 (0.63) | DNMT1DNMT3ADNMT3LEHMT1USP2 | |
| SCHEMBL24004050 | 0.89 | DNMT1 (0.61) | DNMT1DNMT3ADNMT3LEHMT1RIPK2 | |
| SCHEMBL25820561 | 0.86 | DNMT1 (0.68) | DNMT1DNMT3ADNMT3LEHMT1MAPK14 | |
| SCHEMBL25819893 | 0.86 | DNMT1 (0.68) | DNMT1DNMT3ADNMT3LEHMT1USP2 | |
| SCHEMBL25820897 | 0.86 | DNMT1 (0.68) | DNMT1DNMT3ADNMT3LEHMT1MAPK14 | |
| SCHEMBL25819896 | 0.85 | DNMT1 (0.69) | DNMT1DNMT3ADNMT3LEHMT1USP2 | |
| SCHEMBL24009936 | 0.85 | DNMT1 (0.58) | DNMT1DNMT3ADNMT3LEHMT1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | DNMT1 4335/4885DNMT3A 4603/4885DNMT3L 4609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.