Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 7/20 | 0.51 |
| ▸ | DNMT3A | Q9Y6K1 | 6/20 | 0.51 |
| ▸ | BRAF | P15056 | 2/20 | 0.47 |
| ▸ | DNMT3L | Q9UJW3 | 4/20 | 0.45 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.44 |
| ▸ | CCNC | P24863 | 2/20 | 0.43 |
| ▸ | CDK8 | P49336 | 2/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | GAK | O14976 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.41 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25487277 | 0.95 | DNMT1 (0.49) | DNMT1DNMT3ABRAFDNMT3LMAP3K8 | |
| SCHEMBL25820633 | 0.91 | DNMT1 (0.61) | DNMT1DNMT3ABRAFDNMT3LMAP3K8 | |
| SCHEMBL25820602 | 0.90 | DNMT1 (0.51) | DNMT1DNMT3ABRAFDNMT3LABL1 | |
| SCHEMBL24003789 | 0.89 | DNMT1 (0.59) | DNMT1DNMT3ABRAFDNMT3LABL1 | |
| SCHEMBL24010972 | 0.89 | DNMT1 (0.64) | DNMT1DNMT3ABRAFDNMT3LABL1 | |
| SCHEMBL25820730 | 0.89 | DNMT1 (0.64) | DNMT1DNMT3ABRAFDNMT3LABL1 | |
| SCHEMBL25820658 | 0.88 | DNMT1 (0.55) | DNMT1DNMT3ADNMT3LABL1PDGFRB | |
| SCHEMBL24003755 | 0.88 | DNMT1 (0.49) | DNMT1DNMT3ABRAFDNMT3LABL1 | |
| SCHEMBL25820624 | 0.88 | DNMT1 (0.58) | DNMT1DNMT3ABRAFDNMT3LMAP3K8 | |
| SCHEMBL24006001 | 0.88 | MAPT (0.55) | DNMT1DNMT3ADNMT3LEHMT1CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | DNMT1 4335/4885DNMT3A 4603/4885BRAF 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.