Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 7/20 | 0.53 |
| ▸ | DNMT3A | Q9Y6K1 | 6/20 | 0.53 |
| ▸ | DNMT3L | Q9UJW3 | 4/20 | 0.51 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | CCNC | P24863 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LDLR | P01130 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30290879 | 0.95 | DNMT1 (0.52) | DNMT1DNMT3ADNMT3LEHMT1POLB | |
| SCHEMBL24011037 | 0.95 | DNMT1 (0.52) | DNMT1DNMT3ADNMT3LEHMT1POLB | |
| SCHEMBL25820651 | 0.91 | DNMT1 (0.64) | DNMT1DNMT3ADNMT3LEHMT1MEN1 | |
| SCHEMBL25820658 | 0.91 | DNMT1 (0.55) | DNMT1DNMT3ADNMT3LEHMT1POLB | |
| SCHEMBL30290755 | 0.88 | DNMT1 (0.68) | DNMT1DNMT3ADNMT3LEHMT1MAPT | |
| SCHEMBL24011122 | 0.88 | DNMT1 (0.68) | DNMT1DNMT3ADNMT3LEHMT1MAPT | |
| SCHEMBL25820533 | 0.88 | DNMT1 (0.68) | DNMT1DNMT3ADNMT3LEHMT1MAPT | |
| SCHEMBL24003883 | 0.88 | DNMT1 (0.62) | DNMT1DNMT3ADNMT3LEHMT1POLB | |
| SCHEMBL24003803 | 0.87 | DNMT1 (0.52) | DNMT1DNMT3ADNMT3LEHMT1POLB | |
| SCHEMBL25820646 | 0.87 | DNMT1 (0.61) | DNMT1DNMT3ADNMT3LEHMT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | DNMT1 4335/4885DNMT3A 4603/4885DNMT3L 4609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.