Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.45 |
| ▸ | SKP1 | P63208 | 2/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27202974 | 0.86 | CKS1B (0.46) | CKS1BSKP1SKP2ALDH1A1LMNA | |
| SCHEMBL25314946 | 0.82 | MAP4K4 (0.50) | CKS1BSKP1SKP2ALDH1A1LMNA | |
| SCHEMBL31006176 | 0.82 | MAP4K4 (0.50) | CKS1BSKP1SKP2ALDH1A1LMNA | |
| SCHEMBL25322195 | 0.81 | BACE1 (0.48) | CKS1BSKP1SKP2ALDH1A1LMNA | |
| SCHEMBL30218618 | 0.81 | BACE1 (0.48) | CKS1BSKP1SKP2ALDH1A1LMNA | |
| SCHEMBL14551197 | 0.80 | CKS1B (0.45) | CKS1BSKP1SKP2ALDH1A1LMNA | |
| SCHEMBL2851031 | 0.80 | BACE1 (0.46) | CKS1BSKP1SKP2ALDH1A1LMNA | |
| SCHEMBL29790203 | 0.80 | BACE1 (0.49) | CKS1BSKP1SKP2ALDH1A1LMNA | |
| SCHEMBL22912767 | 0.80 | BACE1 (0.49) | CKS1BSKP1SKP2ALDH1A1LMNA | |
| SCHEMBL428233 | 0.79 | GBA1 (0.48) | CKS1BSKP1SKP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023118085-A1 | METHODS OF TREATING BRAIN TUMOURS AND NEUROBLASTOMAS | ASTRAZENECA AB (SE) | 2023-06-29 | — | — | WO | disclosed |