Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.57 |
| ▸ | KCNK3 | O14649 | 8/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CDC25B | P30305 | 2/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25C | P30307 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24010493 | 0.84 | DNMT1 (0.56) | SIRT2KCNK3KCNK9KMT2AMEN1 | |
| SCHEMBL30290816 | 0.84 | DNMT1 (0.56) | SIRT2KCNK3KCNK9KMT2AMEN1 | |
| SCHEMBL25821611 | 0.81 | BRAF (0.49) | KMT2AMEN1 | |
| SCHEMBL25821622 | 0.80 | KCNK3 (0.63) | SIRT2KCNK3KCNK9KMT2AMEN1 | |
| SCHEMBL8940247 | 0.78 | KCNK3 (0.72) | SIRT2KCNK3KCNK9KMT2AMEN1 | |
| SCHEMBL7151866 | 0.78 | KMT2A (0.73) | SIRT2KCNK3KCNK9KMT2AMEN1 | |
| SCHEMBL24010669 | 0.77 | KCNK3 (0.53) | SIRT2KCNK3KCNK9KMT2AMEN1 | |
| SCHEMBL30290811 | 0.77 | KCNK3 (0.53) | SIRT2KCNK3KCNK9KMT2AMEN1 | |
| SCHEMBL27527542 | 0.77 | HDAC2 (0.72) | KMT2AMEN1POLBRAB9ANPC1 | |
| SCHEMBL9481291 | 0.77 | KCNK3 (0.82) | SIRT2KCNK3KCNK9KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | SIRT2 2349/4885KCNK3 2240/4885KCNK9 4540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.