Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.74 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.66 |
| ▸ | TNK1 | Q13470 | 4/20 | 0.53 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2366718 | 0.85 | PARP1 (1.00) | PARP1PARP2KCNH2TNK1TNK2 | |
| Hydrochloric Acid SCHEMBL2366874 | 0.84 | PARP1 (0.98) | PARP1PARP2KCNH2TNK1TNK2 | |
| Hydrochloric Acid SCHEMBL6405673 | 0.83 | PARP1 (0.74) | PARP1PARP2KCNH2TNK1TNK2 | |
| SCHEMBL6409054 | 0.82 | PARP1 (0.58) | PARP1PARP2KCNH2TNK1TNK2 | |
| Hydrochloric Acid SCHEMBL6407095 | 0.81 | PARP1 (0.57) | PARP1PARP2KCNH2TNK1TNK2 | |
| SCHEMBL6405680 | 0.81 | PARP1 (0.64) | PARP1PARP2KCNH2TNK1TNK2 | |
| Hydrochloric Acid SCHEMBL6406628 | 0.79 | PARP1 (0.60) | PARP1PARP2KCNH2TNK1TNK2 | |
| SCHEMBL2385716 | 0.79 | PARP1 (0.84) | PARP1PARP2KCNH2TNK1TNK2 | |
| SCHEMBL6554216 | 0.78 | PARP1 (0.52) | PARP1PARP2KCNH2TNK1TNK2 | |
| Hydrochloric Acid SCHEMBL6409229 | 0.78 | PARP1 (0.55) | PARP1PARP2KCNH2TNK1TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133413-A1 | MULTICYCLIC COMPOUNDS | SLAP PHARMACEUTICALS LLC (US) | 2023-07-13 | — | — | WO | disclosed |