Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.55 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5839879 | 0.86 | ESR1 (0.56) | ESR1ESR2CYP4F2CYP4A11NFKB1 | |
| SCHEMBL7290410 | 0.86 | ESR1 (0.56) | ESR1ESR2CYP4F2CYP4A11NFKB1 | |
| SCHEMBL4193774 | 0.86 | ESR1 (0.56) | ESR1ESR2CYP4F2CYP4A11NFKB1 | |
| SCHEMBL17324786 | 0.84 | POLB (0.49) | ESR1ESR2NFKB1NFKB2RELA | |
| SCHEMBL29052788 | 0.84 | CYP4F2 (0.53) | ESR1ESR2CYP4F2CYP4A11NFKB1 | |
| SCHEMBL22424771 | 0.84 | ESR1 (0.51) | ESR1ESR2CYP4F2CYP4A11NFKB1 | |
| SCHEMBL20876956 | 0.83 | CYP4F2 (0.46) | ESR1ESR2CYP4F2CYP4A11NFKB1 | |
| SCHEMBL13766519 | 0.83 | MLNR (0.49) | CYP4F2CYP4A11NFKB1NFKB2RELA | |
| SCHEMBL3909221 | 0.83 | MLNR (0.49) | CYP4F2CYP4A11NFKB1NFKB2RELA | |
| SCHEMBL13766518 | 0.83 | MLNR (0.49) | CYP4F2CYP4A11NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3606522-B1 | NOVEL TREATMENT OF MITOCHONDRIAL DISEASES | KHONDRION IP B V (NL) | 2023-07-12 | — | — | EP | disclosed |