Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25822333 | 0.89 | HTR2A (0.32) | HTR2AMTNR1AMTNR1BHTR1ASLC6A4 | |
| SCHEMBL29903159 | 0.84 | CYP1A2 (0.35) | GRM5CYP1A2CYP2A6MAPT | |
| SCHEMBL23409334 | 0.84 | CYP1A2 (0.35) | GRM5CYP1A2CYP2A6MAPT | |
| SCHEMBL29903155 | 0.81 | GRM5 (0.36) | GRM5CYP1A2CYP2A6MAPT | |
| SCHEMBL23409337 | 0.81 | GRM5 (0.36) | GRM5CYP1A2CYP2A6MAPT | |
| SCHEMBL25824422 | 0.80 | AKR1B1 (0.37) | HTR2AMTNR1AMTNR1BAKR1B1HTR2C | |
| SCHEMBL29418746 | 0.80 | GRM5 (0.33) | GRM5CYP1A2CYP2A6MAPT | |
| SCHEMBL23043033 | 0.80 | NPC1 (0.33) | GRM5CYP1A2CYP2A6MAPT | |
| SCHEMBL22208168 | 0.80 | GRM5 (0.33) | GRM5CYP1A2CYP2A6MAPT | |
| SCHEMBL29914173 | 0.80 | NPC1 (0.33) | GRM5CYP1A2CYP2A6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125989-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |